Cancer is an extremely diverse disease, with genetic variations among different individuals, tumor types, and inherited populations. These genetic variations can impact the type of disease, its aggressiveness, and the response to treatment. It is important that researchers have precise tools and model systems to research on how these variations impact cancer development and invent effective therapies for individuals of all genetic backgrounds.
In a novel paper available online in the journal Cancer Research, researchers from the Moffitt Cancer Center, in partnership with scientists from Ponce Health Sciences University, Puerto Rico, investigated this subject. They invented an online tool that can be employed to determine the genetic ancestral origin of over 1300 diverse cell lines. In cancer study, cell lines established from patient tumors are employed in laboratory tests as standard systems to comprehend the cellular and molecular basis of cancer, spot therapeutic targets, and grow novel treatments.
On a similar note, researchers disclosed that they have developed a novel imaging technology. Reportedly, this technology can visualize what cells eat. This research might assist in the diagnosis and treatment of diseases including cancer. The research team disclosed that it has devised chemical probes with an ability to light up when they attach to particular molecules that cells eat, for instance, glucose.
Researchers stated that they employed microscopes to see cells eating glucose inside embryos of live zebrafish, which are easy to monitor as they are transparent. They discovered that the system worked well with human cells that are developed in the lab. The team states that their approach might easily be acclimatized to observe other molecules that are critical for health and disease. Researchers proclaimed that the novel technology might help detect small alterations in cells’ eating habits inside the body tissues. This will make it easier to find out diseases sooner.